Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873879 | 0.85 | GPR35 (0.43) | ALDH1A1HPGDTSHRGPR35SMN1; SMN2 | |
| SCHEMBL10820841 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDTSHRGPR35KDM4E | |
| SCHEMBL874301 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL882483 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4E | |
| SCHEMBL10820886 | 0.73 | ALDH1A1 (0.55) | ALDH1A1HPGDTSHRKDM4EGAA | |
| SCHEMBL874117 | 0.71 | RAB9A (0.48) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL29877075 | 0.70 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRGPR35KDM4E | |
| SCHEMBL1778181 | 0.69 | ALDH1A1 (0.55) | ALDH1A1HPGDTSHRGPR35KDM4E | |
| SCHEMBL625723 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HPGDTSHRGPR35KDM4E | |
| SCHEMBL874785 | 0.69 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EGAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |