Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL449604 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1MCOLN3KCNQ3 | |
| SCHEMBL515422 | 0.86 | PTPN1 (0.35) | SMN1; SMN2KMT2AMEN1MCOLN3ALDH1A1 | |
| SCHEMBL515828 | 0.79 | PTPN1 (0.36) | KMT2AMEN1ALDH1A1THRBHPGD | |
| SCHEMBL15839585 | 0.78 | SLC6A3 (0.31) | KMT2AMEN1KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL2122883 | 0.77 | L3MBTL1 (0.40) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL447364 | 0.74 | NOS3 (0.31) | — | |
| SCHEMBL449517 | 0.73 | LMNA (0.37) | SMN1; SMN2ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL2121260 | 0.71 | TDP1 (0.32) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL449804 | 0.70 | F2 (0.31) | — | |
| SCHEMBL449805 | 0.70 | F2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846619-B2 | Artificial oxygen transport protein | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2429979-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065133-A1 | Artificial Oxygen Transport Protein | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2012-03-15 | — | — | US | disclosed |
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010102133-A1 | ARTIFICIAL OXYGEN TRANSPORT PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065133-A1 | Artificial Oxygen Transport Protein | SLC25A21, HSPD1, COX15 | SMN1; SMN2 2958/4885KMT2A 4078/4885MEN1 3973/4885 |
| US-20120065066-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | SMN1; SMN2 2952/4885KMT2A 674/4885MEN1 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.