Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 5/20 | 0.59 |
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.59 |
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.59 |
| ▸ | CA9 | Q16790 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928532 | 1.00 | CA12 (0.59) | CA12CA1CA2CA9LMNA | |
| SCHEMBL29349737 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9LMNA | |
| SCHEMBL29351462 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9LMNA | |
| SCHEMBL1234749 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9LMNA | |
| SCHEMBL1079927 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11730543 | 0.95 | CA12 (0.60) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9624141 | 0.90 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9624135 | 0.90 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL30462508 | 0.90 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8746487 | 0.89 | CA12 (0.56) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237119-B2 | Stable liquid detergent composition containing hydrophobic brightener | PROCTER & GAMBLE (US) | 1997-02-19 | — | — | EP | claimed |
| EP-0167205-B1 | STABLE LIQUID DETERGENTS CONTAINING ANIONIC SURFACTANT AND MONOSULFONATED BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-11 | — | — | EP | claimed |
| US-4970029-A | MONOSULFONATED NAPHTHOTRIAZINE STILBENE BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1990-11-13 | — | — | US | claimed |
| EP-0167205-A2 | Stable liquid detergents containing anionic surfactant and monosulfonated brightener | THE PROCTER & GAMBLE COMPANY (US) | 1986-01-08 | — | — | EP | claimed |
| US-4559169-A | STILBENE SULFONATE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-17 | — | — | US | claimed |
| EP-0237119-B2 | Stable liquid detergent composition containing hydrophobic brightener | PROCTER & GAMBLE (US) | 1997-02-19 | — | — | EP | disclosed |
| EP-0167205-B1 | STABLE LIQUID DETERGENTS CONTAINING ANIONIC SURFACTANT AND MONOSULFONATED BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0167205-A2 | Stable liquid detergents containing anionic surfactant and monosulfonated brightener | THE PROCTER & GAMBLE COMPANY (US) | 1986-01-08 | — | — | EP | disclosed |
| US-4559169-A | STILBENE SULFONATE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-17 | — | — | US | disclosed |
| US-4559169-A | STILBENE SULFONATE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-17 | — | — | US | disclosed |