SCHEMBL8747696

SCHEMBL8747696

O=C(Cl)c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
NT5E P21589 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.45
POLB P06746 1/20 0.42
CYP2D6 P10635 1/20 0.42
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
KMT2A Q03164 1/20 0.41
TIMP3 P35625 1/20 0.41
CA2 P00918 3/20 0.40
CA1 P00915 2/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CYP2C19 P33261 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9659082 0.98 LMNA (0.50) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL724893 0.83 ALDH1A1 (0.50) LMNAALDH1A1TSHRPOLBKMT2A
SCHEMBL11475588 0.81 TSHR (0.57) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL30585652 0.81 RXRA (0.38) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL35155 0.81 ALDH1A1 (0.48) LMNAALDH1A1TDP1POLBKMT2A
SCHEMBL11587522 0.80 LMNA (0.56) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL11587552 0.80 LMNA (0.56) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL599583 0.79 ENPP2 (0.54)
SCHEMBL497483 0.79 CA2 (0.65) CA2CA1CA12CA3CA6
SCHEMBL1762291 0.79 ALDH1A1 (0.47) ALDH1A1TSHRCYP2D6KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5644017-A SOLVENT RESISTANCE, FLAME RESISTANCE, MOLDING MATERIALS THE DOW CHEMICAL COMPANY (US) 1997-07-01 US disclosed
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0442638-B1 Polymeric compounds DU PONT UK (GB) 1996-07-10 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5278022-A Photopolymerizable E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-11 US disclosed
EP-0358400-B1 Improvements in or relating to polymeric compounds DU PONT (US) 1993-11-10 EP disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5120799-A POLYMERIC COMPOUNDS HAVING PENDANT SULPHONATO GROUPS AND METHOD OF PRODUCING THE POLYMERIC COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (INC.) (US) 1992-06-09 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0442638-A2 Polymeric compounds Du Pont (UK) Limited (GB) 1991-08-21 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed
US-4215114-A Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be THE UPJOHN COMPANY (US) 1980-07-29 US disclosed
US-4197308-A Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides THE UPJOHN COMPANY (US) 1980-04-08 US disclosed
US-4192885-A Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkylamino]cycloaliphatic}cyanobenzamides THE UPJOHN COMPANY (US) 1980-03-11 US disclosed
US-4179501-A Analgesic N-(2-aminocycloaliphatic)azidobenzamides THE UPJOHN COMPANY (US) 1979-12-18 US disclosed
US-4153717-A 260/332.2 R THE UPJOHN COMPANY (US) 1979-05-08 US disclosed
US-4152459-A Analgesic N-2-(aminocycloaliphatic)-hydroxy, alkoxy and (allylic)alkenyloxy-benzamides THE UPJOHN COMPANY (US) 1979-05-01 US disclosed
US-4148914-A Analgesic N-(2-aminocyclo aliphatic)cyanobenzamides THE UPJOHN COMPANY (US) 1979-04-10 US disclosed
US-4098904-A ANALGESIC N-(2-AMINOCYCLOALIPHATIC)BENZAMIDES THE UPJOHN COMPANY (US) 1978-07-04 US disclosed