Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39777 | 0.98 | ALDH1A1 (0.55) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL114655 | 0.94 | TSHR (0.48) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL24370755 | 0.83 | GAA (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8812313 | 0.80 | DGKA (0.38) | ALDH1A1LMNATSHR | |
| SCHEMBL446542 | 0.79 | LMNA (0.65) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL7748806 | 0.77 | TSHR (0.67) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6899202 | 0.77 | TSHR (0.67) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL9661395 | 0.77 | TSHR (0.67) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL21357404 | 0.77 | TSHR (0.67) | ALDH1A1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6367297 | 0.77 | TSHR (0.67) | ALDH1A1LMNATSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279248-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2024-08-22 | — | — | US | disclosed |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | MELINTA SUBSIDIARY CORP. (US) | 2024-06-04 | — | — | US | disclosed |
| CN-111556872-B | Synthesis of borate derivatives and uses thereof | 梅琳塔治疗公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-4356736-A2 | SYNTHESIS OF BORONATE SALTS | Melinta Therapeutics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3604316-B1 | SYNTHESIS OF BORONATE SALTS | MELINTA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | disclosed |
| CN-116199658-A | Synthesis method and application of modified long-chain fatty acid type PET reagent precursor | 北京先通国际医药科技股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-116041169-A | Process route for synthesizing key intermediate of modified fatty acid type PET reagent precursor and application thereof | 北京先通国际医药科技股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115141125-B | Synthesis method and application of modified long-chain fatty acid type PET reagent precursor | 北京先通国际医药科技股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| US-20200308197-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2020-10-01 | — | — | US | disclosed |
| EP-3704130-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | Melinta Therapeutics, Inc. (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-3604316-A1 | SYNTHESIS OF BORONATE SALTS | Rempex Pharmaceuticals, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| US-20200031851-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2020-01-30 | — | — | US | disclosed |
| US-10385074-B2 | Synthesis of boronate salts and uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2019-08-20 | — | — | US | disclosed |
| EP-3140310-B1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | REMPEX PHARMACEUTICALS INC (US) | 2019-08-07 | — | — | EP | disclosed |
| US-20190127396-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | CORTLAND CAPITAL MARKET SERVICES LLC, AS AGENT | 2019-05-02 | — | — | US | disclosed |
| EP-3140310-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | Rempex Pharmaceuticals, Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170057979-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2017-03-02 | — | — | US | disclosed |
| WO-2015171430-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2015-11-12 | — | — | WO | disclosed |
| US-20120095211-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095211-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | VIP, EIF2AK2, PREP | ALDH1A1 1706/4885LMNA 947/4885TSHR 4451/4885 |
| US-20200031851-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | BTD, BCL6B, BRI3BP | ALDH1A1 3175/4885LMNA 2796/4885TSHR 3061/4885 |
| US-20170057979-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | BTD, BCL6B, BRI3BP | ALDH1A1 3175/4885LMNA 2796/4885TSHR 3061/4885 |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | ADH5, ADH1A, ADH7 | ALDH1A1 69/4885LMNA 4411/4885TSHR 2507/4885 |
| US-20240279248-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | ADH5, ADH1A, ADH7 | ALDH1A1 69/4885LMNA 4411/4885TSHR 2507/4885 |
| US-10385074-B2 | Synthesis of boronate salts and uses thereof | BTD, BCL6B, BRI3BP | ALDH1A1 3175/4885LMNA 2796/4885TSHR 3061/4885 |
| US-20200308197-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | ADH5, ADH1A, ADH7 | ALDH1A1 69/4885LMNA 4411/4885TSHR 2507/4885 |
| US-20190127396-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | ADH5, ADH1A, ADH7 | ALDH1A1 69/4885LMNA 4411/4885TSHR 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.