Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767658 | 0.79 | NPC1 (0.44) | NPC1RAB9AKMT2AMEN1GPR55 | |
| SCHEMBL11513541 | 0.73 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL4317705 | 0.70 | PKM (0.44) | NPC1RAB9AKMT2AMEN1PKM | |
| SCHEMBL4314794 | 0.70 | PKM (0.44) | NPC1RAB9AKMT2AMEN1PKM | |
| SCHEMBL8767268 | 0.66 | TRPA1 (0.41) | — | |
| SCHEMBL2132367 | 0.65 | L3MBTL1 (0.60) | TSHRNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL917005 | 0.64 | L3MBTL1 (0.68) | KDM4ENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7389188 | 0.64 | L3MBTL1 (0.73) | TSHRNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8882276 | 0.63 | L3MBTL1 (0.57) | KDM4ETSHRNPC1RAB9AKMT2A | |
| SCHEMBL5872163 | 0.63 | L3MBTL1 (0.71) | KDM4ENPC1RAB9AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | disclosed |