Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314794 | 1.00 | PKM (0.44) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7083850 | 0.76 | PKM (0.39) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL26118448 | 0.74 | CASP3 (0.51) | RAB9AALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL30630076 | 0.74 | CASP3 (0.51) | RAB9AALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL14461626 | 0.74 | POLB (0.42) | PKMALDH1A1POLB | |
| SCHEMBL11513541 | 0.72 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL8767658 | 0.71 | NPC1 (0.44) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL4036783 | 0.70 | PKM (0.57) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8766491 | 0.70 | KDM4E (0.41) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10245222 | 0.70 | TSHR (0.43) | MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131707-A1 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2009-05-21 | — | — | US | disclosed |
| US-7452999-B2 | Chemical process for the preparation of intermediates to obtain N-formyl hydroxy-lamine compounds | NOVARTIS AG (CH) | 2008-11-18 | — | — | US | disclosed |
| US-20070179298-A1 | Chemical process for the preparation of intermediates to obtain n-formyl hydroxy-lamine compounds | NOVARTIS AG (CH) | 2007-08-02 | — | — | US | disclosed |
| EP-1599440-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis AG (CH) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076053-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131707-A1 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | HAO2, HAO1, HAAO | PKM 1599/4885NPC1 4335/4885RAB9A 4399/4885 |
| US-20070179298-A1 | Chemical process for the preparation of intermediates to obtain n-formyl hydroxy-lamine compounds | HAO1, LMNA, HAO2 | PKM 1083/4885NPC1 3232/4885RAB9A 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.