Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 6/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124088 | 0.87 | HMGCR (0.47) | NR1H4FDPSRIPK1ALOX5PTGS1 | |
| SCHEMBL8767384 | 0.78 | NR1H4 (0.45) | NR1H4FDPSRIPK1ALOX5PTGS1 | |
| SCHEMBL8150112 | 0.72 | ALDH1A1 (0.43) | NR1H4RIPK1ALOX5PTGS1PTGS2 | |
| SCHEMBL7123113 | 0.71 | PKM (0.41) | ALDH1A1TP53MAPTALOX15NPSR1 | |
| SCHEMBL7122163 | 0.69 | NR1H4 (0.42) | NR1H4RIPK1ALOX5PTGS1PTGS2 | |
| SCHEMBL7128467 | 0.69 | ALOX5 (0.46) | NR1H4FDPSALOX5PTGS1PTGS2 | |
| SCHEMBL8142160 | 0.69 | LMNA (0.46) | NR1H4ALOX5PTGS1PTGS2LMNA | |
| SCHEMBL8766605 | 0.69 | FDPS (0.41) | FDPSLMNAGAAMEN1KMT2A | |
| SCHEMBL8003353 | 0.69 | HMGCR (0.47) | NR1H4ALOX5PTGS1PTGS2LMNA | |
| SCHEMBL7127837 | 0.68 | GAA (0.38) | LMNAALDH1A1TP53MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |