Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768071 | 0.81 | CA2 (0.44) | — | |
| SCHEMBL8768660 | 0.68 | CYP3A4 (0.39) | — | |
| SCHEMBL9014507 | 0.65 | HMGCR (0.33) | — | |
| SCHEMBL8768079 | 0.64 | PPARG (0.46) | — | |
| SCHEMBL9856113 | 0.64 | LTA4H (0.63) | LTA4HESR1 | |
| SCHEMBL8922447 | 0.63 | PPARA (0.51) | — | |
| SCHEMBL4175772 | 0.63 | MAPK1 (0.39) | — | |
| SCHEMBL8768706 | 0.62 | CA2 (0.49) | ESR1 | |
| SCHEMBL18201982 | 0.61 | LMNA (0.53) | — | |
| SCHEMBL23007619 | 0.61 | ESR1 (0.55) | LTA4HESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | disclosed |
| EP-0621255-A1 | Substituted phenoxy-isobutyric acids and esters | ADIR ET COMPAGNIE (FR) | 1994-10-26 | — | — | EP | disclosed |