SCHEMBL8769941

SCHEMBL8769941

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)c1ccc(Br)cc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
LMNA P02545 1/20 0.40
CYP2A6 P11509 1/20 0.36
TRPV1 Q8NER1 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3963219 1.00 CA1 (0.41) CA1CA2CA5ACA9LMNA
SCHEMBL7138748 1.00 CA1 (0.41) CA1CA2CA5ACA9LMNA
SCHEMBL5143771 0.98 CA1 (0.42) CA1CA2CA5ACA9LMNA
SCHEMBL19056950 0.93 CA1 (0.45) CA1CA2CA5ACA9CYP2A6
SCHEMBL14577302 0.91 CA1 (0.43) CA1CA2CA5ACA9LMNA
SCHEMBL19056952 0.91 CA1 (0.46) CA1CA2CA5ACA9CYP2A6
SCHEMBL673282 0.88 LMNA (0.43) CA1CA2LMNA
SCHEMBL5239662 0.85 CA1 (0.46) CA1CA2CA5ACA9CYP2A6
Biphenyl SCHEMBL6131233 0.85 ALDH1A1 (0.48) CA1CA2CA5ACA9TRPV1
SCHEMBL2963352 0.81 ALDH1A1 (0.42) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026327-B Polymer matrix with ionic additives 3M创新有限公司 2022-07-05 CN disclosed
EP-3319947-B1 SUBSTITUTED BENZOTRIAZOLE PHENOLS 3M INNOVATIVE PROPERTIES CO (US) 2022-05-04 EP disclosed
CN-108026054-B Substituted benzotriazolols 3M创新有限公司 2021-10-15 CN disclosed
US-11078419-B2 Substituted benzotriazole phenolate salts and antioxidant compositions formed therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-08-03 US disclosed
US-11053373-B2 Polymeric matrices with ionic additives 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-07-06 US disclosed
EP-3320055-B1 SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM 3M INNOVATIVE PROPERTIES CO (US) 2021-03-03 EP disclosed
US-10919867-B2 Substituted benzotriazole phenols 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-02-16 US disclosed
CN-107849449-B Substituted benzotriazole phenolates and antioxidant compositions formed therefrom 3M创新有限公司 2020-12-29 CN disclosed
CN-108026679-B Electret webs with charge-enhancing additives 3M创新有限公司 2020-10-16 CN disclosed
US-10724171-B2 Electret webs with charge-enhancing additives 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-07-28 US disclosed
US-20180195000-A1 SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2018-07-12 US disclosed
EP-2829542-B1 BENZOBIS(THIADIAZOLE) DERIVATIVE AND ORGANIC ELECTRONICS DEVICE USING SAME UBE INDUSTRIES (JP) 2018-07-11 EP disclosed
US-20180186757-A1 SUBSTITUTED BENZOTRIAZOLE PHENOLS 3M INNOVATIVE PROPERTIES COMPANY 2018-07-05 US disclosed
US-9290516-B2 Benzobis(thiadiazole) derivative and organic electronics device comprising same UBE INDUSTRIES, LTD. (JP) 2016-03-22 US disclosed
US-20150059853-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE AND ORGANIC ELECTRONICS DEVICE COMPRISING SAME FUTURE INK CORPORATION (JP) 2015-03-05 US disclosed
EP-2829542-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE AND ORGANIC ELECTRONICS DEVICE USING SAME UBE Industries, Ltd. (JP) 2015-01-28 EP disclosed
EP-0629205-B1 INTERMEDIATES FOR THERMALLY STABLE, FLUORINE-CONTAINING POLYSILOXANES AND GLASS FIBER COATED THEREWITH DU PONT (US) 1997-09-10 EP disclosed
EP-0629205-A1 THERMALLY STABLE, FLUORINE-CONTAINING ORGANOSILANES. DU PONT (US) 1994-12-21 EP disclosed
WO-1993020084-A1 THERMALLY STABLE, FLUORINE-CONTAINING ORGANOSILANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-10-14 WO disclosed
US-5180845-A Intermediates for bonding fluoropolymers to glass fibers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180186757-A1 SUBSTITUTED BENZOTRIAZOLE PHENOLS TYR, COMT, TH CA1 3742/4885CA2 2740/4885CA5A 3666/4885
US-10919867-B2 Substituted benzotriazole phenols TYR, COMT, TH CA1 3742/4885CA2 2740/4885CA5A 3666/4885
US-11078419-B2 Substituted benzotriazole phenolate salts and antioxidant compositions formed therefrom COMT, OGFOD1, TYR CA1 3359/4885CA2 1390/4885CA5A 2280/4885
US-20180195000-A1 SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM COMT, OGFOD1, TYR CA1 3359/4885CA2 1390/4885CA5A 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.