Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138748 | 1.00 | CA1 (0.41) | CA1CA2CA5ACA9LMNA | |
| SCHEMBL8769941 | 1.00 | CA1 (0.41) | CA1CA2CA5ACA9LMNA | |
| SCHEMBL5143771 | 0.98 | CA1 (0.42) | CA1CA2CA5ACA9LMNA | |
| SCHEMBL19056950 | 0.93 | CA1 (0.45) | CA1CA2CA5ACA9CYP2A6 | |
| SCHEMBL14577302 | 0.91 | CA1 (0.43) | CA1CA2CA5ACA9LMNA | |
| SCHEMBL19056952 | 0.91 | CA1 (0.46) | CA1CA2CA5ACA9CYP2A6 | |
| SCHEMBL673282 | 0.88 | LMNA (0.43) | CA1CA2LMNA | |
| SCHEMBL5239662 | 0.85 | CA1 (0.46) | CA1CA2CA5ACA9CYP2A6 | |
| Biphenyl SCHEMBL6131233 | 0.85 | ALDH1A1 (0.48) | CA1CA2CA5ACA9TRPV1 | |
| SCHEMBL2963352 | 0.81 | ALDH1A1 (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399684-B2 | Sulfonamide-based organocatalysts and method for their use | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2013-03-19 | — | — | US | disclosed |
| US-7576245-B2 | Fluorous tagging and scavenging reactants and methods of synthesis and use thereof | FLUOROUS TECHNOLOGIES INCORPORATED (US) | 2009-08-18 | — | — | US | disclosed |
| WO-2009039181-A2 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OR. STATE UNIV. (US) | 2009-03-26 | — | — | WO | disclosed |
| US-20060128957-A1 | Fluorous tagging and scavenging reactants and methods of synthesis and use thereof | FLUOROUS TECHNOLOGIES INCORPORATED | 2006-06-15 | — | — | US | disclosed |
| US-7060850-B2 | Fluorous tagging and scavenging reactants and methods of synthesis and use thereof | FLUOROUS TECHNOLOGIES INCORPORATED (US) | 2006-06-13 | — | — | US | disclosed |
| US-20040073054-A1 | New fluorous tagging and scavenging reactants and methods of synthesis and use thereof | FLUOROUS TECHNOLOGIES, INC. | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073054-A1 | New fluorous tagging and scavenging reactants and methods of synthesis and use thereof | THEM6, NOTUM, RNF31 | CA1 3007/4885CA2 3304/4885CA5A 4084/4885 |
| US-20060128957-A1 | Fluorous tagging and scavenging reactants and methods of synthesis and use thereof | PFAS, CTSF, AFF2 | CA1 2947/4885CA2 3196/4885CA5A 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.