SCHEMBL8771955

SCHEMBL8771955

CSc1ccc(OCC(C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44
CA2 P00918 1/20 0.42
TRPA1 O75762 1/20 0.42
MTNR1A P48039 3/20 0.40
MTNR1B P49286 3/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
HRH2 P25021 2/20 0.39
HRH1 P35367 2/20 0.39
ACACB O00763 1/20 0.39
ACACA Q13085 1/20 0.39
BACE1 P56817 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772014 0.84 CTSK (0.53) CTSSCTSKCA2TRPA1
SCHEMBL9227722 0.83 CA2 (0.35) CTSSCTSKCA2TRPA1MTNR1A
SCHEMBL8772005 0.83 CA2 (0.51) CTSSCTSKCA2TRPA1
SCHEMBL8771994 0.83 ALDH1A1 (0.47) CTSSCTSKCA2ALDH1A1
SCHEMBL8771777 0.83 CA2 (0.43) CTSSCTSKCA2TRPA1MTNR1A
SCHEMBL8772006 0.81 CTSS (0.47) CTSSCTSKCA2TRPA1MTNR1A
SCHEMBL8772000 0.76 MMP2 (0.46) CTSSCTSKTRPA1MTNR1AMTNR1B
SCHEMBL27895372 0.76 MTNR1A (0.49) CTSSCTSKCA2MTNR1AMTNR1B
SCHEMBL8771904 0.76 ALDH1A1 (0.46) CTSSCTSKCA2TRPA1KDM4E
SCHEMBL8771755 0.75 CTSS (0.56) CTSSCTSKCA2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648740-B1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-10-08 EP disclosed
EP-0648740-A1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1995-04-19 EP disclosed