Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772392 | 0.83 | PLAAT3 (0.46) | POLBLMNAL3MBTL1PLAAT3PLAAT5 | |
| SCHEMBL8772509 | 0.81 | TSHR (0.44) | POLBSIGMAR1TDP1L3MBTL1MEN1 | |
| SCHEMBL8439618 | 0.77 | GSK3A (0.43) | CCR3SIGMAR1GSK3AGSK3BTDP1 | |
| SCHEMBL8109827 | 0.77 | FAAH (0.43) | CCR3SIGMAR1GSK3AGSK3BTDP1 | |
| SCHEMBL8549722 | 0.77 | HRH3 (0.41) | CCR3SIGMAR1 | |
| SCHEMBL8772475 | 0.76 | FAAH (0.42) | CCR3SIGMAR1GSK3AGSK3BTDP1 | |
| SCHEMBL8772552 | 0.75 | KMT2A (0.41) | POLBLMNAKMT2AALDH1A1 | |
| SCHEMBL8772402 | 0.74 | HTR2A (0.43) | SIGMAR1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL8772398 | 0.74 | GSK3A (0.39) | CCR3SIGMAR1GSK3AGSK3BLMNA | |
| SCHEMBL8772537 | 0.74 | POLB (0.40) | POLBCCR3SIGMAR1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | claimed |