Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426162 | 0.80 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL6353755 | 0.78 | GAA (0.57) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL9646621 | 0.78 | CA2 (0.64) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL7029959 | 0.78 | CA2 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL1149166 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL1148799 | 0.78 | KMT2A (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL10619867 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL5974400 | 0.78 | CA2 (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL3514586 | 0.78 | PLCG1 (0.61) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL798585 | 0.77 | PSIP1 (0.56) | ALDH1A1CA2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574799-B1 | Method for the preparation of fibre-reactive formazana dyes as well as aminophenols | BASF AG (DE) | 1997-09-17 | — | — | EP | disclosed |
| US-5536876-A | Formylamino-aminophenol compounds and their use in preparation of fiber-reactive formazan dyes | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5410027-A | Diazotization of a protectively formylated hydroxyphenylenediamine; coupling with a hydrazone compound; metallization; reacting with a halotriazine | BASF AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | disclosed |
| EP-0574799-A2 | Method for the preparation of fibre-reactive formazana dyes as well as aminophenols | BASF Aktiengesellschaft (DE) | 1993-12-22 | — | — | EP | disclosed |