Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426162 | 0.80 | ALDH1A1 (0.52) | CA2CA1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL2646288 | 0.78 | ALDH1A1 (0.47) | CA2CA1MMP2MMP9ALDH1A1 | |
| SCHEMBL3514586 | 0.78 | PLCG1 (0.61) | CA2CA1MMP2MMP9ALDH1A1 | |
| SCHEMBL1148799 | 0.78 | KMT2A (0.47) | CA2CA1MMP2MMP9ALDH1A1 | |
| SCHEMBL5974400 | 0.78 | CA2 (0.53) | CA2CA1MMP2MMP9ALDH1A1 | |
| SCHEMBL8775111 | 0.78 | ALDH1A1 (0.42) | CA2ALDH1A1MMP8MMP13CYP3A4 | |
| SCHEMBL1149166 | 0.78 | ALDH1A1 (0.69) | CA2CA1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6353755 | 0.78 | GAA (0.57) | CA2CA1MMP2MMP9ALDH1A1 | |
| SCHEMBL7033001 | 0.78 | CA2 (0.64) | CA2CA1MMP2MMP9ALDH1A1 | |
| SCHEMBL798585 | 0.77 | PSIP1 (0.56) | CA2CA1ALDH1A1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841323-B1 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-5902905-A | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0841323-A2 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-05-13 | — | — | EP | disclosed |