Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775912 | 0.81 | CA12 (0.41) | LMNASMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL8775765 | 0.79 | ROCK2 (0.48) | ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL8776121 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8775947 | 0.73 | MAPK1 (0.47) | LMNASMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL8775855 | 0.72 | TBXAS1 (0.54) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8775797 | 0.70 | MMP1 (0.45) | ALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL8775931 | 0.69 | CYP3A4 (0.55) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9877346 | 0.68 | MEN1 (0.62) | ALDH1A1TSHRLMNASMN1; SMN2PTGES | |
| SCHEMBL8775877 | 0.67 | CYP3A4 (0.52) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8775935 | 0.67 | CYP3A4 (0.52) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |