Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775901 | 0.78 | ALDH1A1 (0.47) | MAOBALDH1A1SMN1; SMN2CYP1A1CYP1A2 | |
| SCHEMBL8775896 | 0.76 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A | |
| SCHEMBL27662708 | 0.75 | CFTR (0.43) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30218733 | 0.74 | LMNA (0.68) | MAOAMAOBALDH1A1SMN1; SMN2CYP1A1 | |
| SCHEMBL2531633 | 0.74 | LMNA (0.68) | MAOAMAOBALDH1A1SMN1; SMN2CYP1A1 | |
| SCHEMBL8775947 | 0.73 | MAPK1 (0.47) | SLC6A2SLC6A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL7284897 | 0.73 | MAOA (0.50) | MAOAMAOBALDH1A1SRC | |
| SCHEMBL8775748 | 0.72 | ALOX5 (0.63) | ALDH1A1KCNA5HTT | |
| SCHEMBL27748512 | 0.72 | CFTR (0.52) | SLC6A2SLC6A4SLC6A3CFTRGOPC | |
| SCHEMBL8775843 | 0.72 | SLC6A2 (0.46) | MAOAMAOBSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |