Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728356 | 0.90 | MAPT (0.51) | PTGER4PTGER2MAPTPOLBALDH1A1 | |
| SCHEMBL9088952 | 0.83 | PTGER4 (0.51) | PTGER4PTGER2MAPTALDH1A1SIGMAR1 | |
| SCHEMBL8777936 | 0.79 | TP53 (0.52) | MAPTPOLBALDH1A1LMNATP53 | |
| SCHEMBL8778095 | 0.79 | FFAR1 (0.47) | MAPTPOLBALDH1A1LMNATP53 | |
| SCHEMBL9597610 | 0.78 | PTGER4 (0.47) | PTGER4PTGER2MAPTALDH1A1LMNA | |
| SCHEMBL30104666 | 0.78 | ALDH1A1 (0.68) | POLBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8245692 | 0.78 | ALDH1A1 (0.68) | POLBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8778079 | 0.77 | PTGER4 (0.49) | PTGER4PTGER2MAPTALDH1A1 | |
| SCHEMBL8778007 | 0.76 | LMNA (0.50) | ALDH1A1LMNATP53THRB | |
| SCHEMBL16494249 | 0.74 | ACHE (0.55) | MAPTPOLBALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651743-B1 | INDOLINYL N-HYDROXYUREA AND N-HYDROXAMIC ACID DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1997-12-17 | — | — | EP | disclosed |