SCHEMBL8778253

SCHEMBL8778253

CC(=O)ON(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.46
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
TSHR P16473 2/20 0.43
ALDH1A1 P00352 4/20 0.43
HPGD P15428 2/20 0.43
HSD11B1 P28845 1/20 0.43
CYP3A4 P08684 1/20 0.42
DEPTOR Q8TB45 1/20 0.42
F2 P00734 1/20 0.41
LMNA P02545 1/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
POLB P06746 1/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8778087 0.92 ELANE (0.43) ELANECES2CES1TSHRALDH1A1
SCHEMBL13604121 0.82 HSD11B1 (0.46) ELANECES2CES1TSHRALDH1A1
SCHEMBL8778288 0.81 LMNA (0.54) CES2CES1TSHRALDH1A1F2
SCHEMBL10996635 0.80 ELANE (0.43) ELANECES2CES1TSHRALDH1A1
SCHEMBL1951213 0.80 ALDH1A1 (0.44) ELANECES2CES1TSHRALDH1A1
SCHEMBL13479807 0.78 TSHR (0.52) CES2CES1TSHRALDH1A1HPGD
SCHEMBL2363903 0.77 ALDH1A1 (0.42) ELANECES2CES1TSHRALDH1A1
SCHEMBL3183842 0.76 ALDH1A1 (0.49) ELANECES2CES1ALDH1A1HPGD
SCHEMBL8778128 0.76 CES2 (0.53) CES2CES1TSHRALDH1A1HPGD
SCHEMBL3192317 0.74 MLYCD (0.40) ELANECES2CES1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576622-B1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK CO (US) 1997-11-05 EP disclosed
EP-0576622-A1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
WO-1992017821-A1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1992-10-15 WO disclosed
US-5141839-A LITHOGRAPHIC PRINTING PLATES HAVING A RADIATION-SENSITIVE LAYER COMPRISING A PHOTOCROSSLINKABLE POLYMER, A LEUCO DYE, A PHOTOOXIDANT AND A HETEROAROMATIC AMINE N-OXIDE EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed
US-5141842-A Negative working lithography printing plates EASTMAN KODAK COMPANY (US) 1992-08-25 US disclosed