Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779244 | 0.86 | LTA4H (0.44) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8779132 | 0.86 | ACACB (0.34) | ALDH1A1CYP2C19MAPTHSD17B10 | |
| SCHEMBL8779023 | 0.85 | KDM4E (0.36) | KMT2ASMN1; SMN2CYP1A2MAPTKDM4E | |
| SCHEMBL8779296 | 0.84 | MEN1 (0.33) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8779424 | 0.83 | MAPK8 (0.37) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8779185 | 0.83 | ACACB (0.37) | MEN1KMT2ARAB9ATSHRALDH1A1 | |
| SCHEMBL8881461 | 0.81 | MEN1 (0.44) | MEN1KMT2ARAB9ATSHRNPC1 | |
| SCHEMBL8779178 | 0.80 | PRKD3 (0.33) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8779309 | 0.80 | L3MBTL1 (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL8779250 | 0.79 | MEN1 (0.42) | MEN1KMT2ARAB9ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |