Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779184 | 0.89 | MAOB (0.39) | PARP10LMNARAB9AMEN1KMT2A | |
| SCHEMBL8779196 | 0.89 | MAOB (0.37) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8779211 | 0.86 | MEN1 (0.40) | PARP10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8785041 | 0.85 | LTA4H (0.42) | LTA4HLMNAHPGDNPC1RAB9A | |
| SCHEMBL8779424 | 0.83 | MAPK8 (0.37) | PARP10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8779132 | 0.81 | ACACB (0.34) | LMNA | |
| SCHEMBL8882670 | 0.81 | LTA4H (0.46) | LTA4HMCL1PARP10LMNAHPGD | |
| SCHEMBL8779178 | 0.80 | PRKD3 (0.33) | HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8779023 | 0.80 | KDM4E (0.36) | SMN1; SMN2KMT2A | |
| SCHEMBL8779309 | 0.80 | L3MBTL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |