Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779092 | 0.90 | ALDH1A1 (0.41) | LNPEPALDH1A1GRM2MEN1KMT2A | |
| SCHEMBL8779162 | 0.90 | ALDH1A1 (0.41) | LNPEPALDH1A1GRM2MEN1KMT2A | |
| SCHEMBL8779223 | 0.88 | AAK1 (0.39) | LARS1AAK1CIT | |
| SCHEMBL8779220 | 0.86 | AAK1 (0.40) | LNPEPLARS1AAK1CIT | |
| SCHEMBL8779387 | 0.82 | AAK1 (0.38) | LARS1AAK1CIT | |
| SCHEMBL8779239 | 0.81 | LNPEP (0.40) | LNPEPAAK1 | |
| SCHEMBL8779250 | 0.81 | MEN1 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8779164 | 0.80 | KDM4E (0.39) | ALDH1A1CITANPEP | |
| SCHEMBL8779204 | 0.80 | KDM4E (0.39) | ALDH1A1CITANPEP | |
| SCHEMBL8779075 | 0.80 | OPRK1 (0.41) | ALDH1A1CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |