Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779184 | 0.89 | MAOB (0.39) | MAOBNR4A2MAOAKMT2ARAB9A | |
| SCHEMBL8779244 | 0.89 | LTA4H (0.44) | KMT2ANPC1RAB9ALMNAMEN1 | |
| SCHEMBL8882247 | 0.82 | SMPD1 (0.41) | MAOBSMPD1NR4A2ADORA3MAOA | |
| SCHEMBL8779424 | 0.81 | MAPK8 (0.37) | MAOBMAOAKMT2ANPC1RAB9A | |
| SCHEMBL8779132 | 0.79 | ACACB (0.34) | ADORA3ADORA1LMNAUBE2NALDH1A1 | |
| SCHEMBL8779023 | 0.78 | KDM4E (0.36) | SMPD1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8779309 | 0.78 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL8779178 | 0.78 | PRKD3 (0.33) | SMPD1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8779168 | 0.78 | SMN1; SMN2 (0.40) | MAOBNR4A2MAOAKMT2ALMNA | |
| SCHEMBL8779211 | 0.77 | MEN1 (0.40) | KMT2ANPC1RAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |