Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779122 | 0.88 | MAPT (0.33) | CARM1 | |
| SCHEMBL8779326 | 0.87 | SMN1; SMN2 (0.39) | CARM1 | |
| SCHEMBL8779231 | 0.85 | CARM1 (0.33) | NFKB1NFKB2RELACARM1 | |
| SCHEMBL8779273 | 0.85 | IKBKB (0.38) | CARM1 | |
| SCHEMBL8779138 | 0.84 | SMN1; SMN2 (0.39) | NFKB1NFKB2RELA | |
| SCHEMBL8779210 | 0.84 | CIT (0.30) | NFKB1NFKB2RELA | |
| SCHEMBL8779241 | 0.83 | LMNA (0.40) | NFKB1NFKB2RELA | |
| SCHEMBL8779283 | 0.82 | ALDH1A1 (0.35) | — | |
| SCHEMBL8779387 | 0.82 | AAK1 (0.38) | — | |
| SCHEMBL8779253 | 0.82 | HTT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |