Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780785 | 0.88 | HRH3 (0.40) | KCNH2CYP19A1 | |
| SCHEMBL8780789 | 0.87 | ADORA2A (0.41) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780829 | 0.87 | RIPK2 (0.43) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780892 | 0.87 | RXFP1 (0.42) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780909 | 0.85 | KCNH2 (0.42) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780837 | 0.84 | L3MBTL1 (0.45) | ADORA3ADORA2AADORA2BADORA1MCHR1 | |
| SCHEMBL8780998 | 0.84 | SLC6A4 (0.42) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780919 | 0.84 | HRH3 (0.41) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780862 | 0.83 | KCNH2 (0.59) | KCNH2ALK | |
| SCHEMBL8780776 | 0.82 | MAOA (0.37) | ADORA3ADORA2AADORA2BADORA1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |