Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TCF4 | P15884 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780909 | 0.91 | KCNH2 (0.42) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780892 | 0.88 | RXFP1 (0.42) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780789 | 0.86 | ADORA2A (0.41) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780829 | 0.86 | RIPK2 (0.43) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780756 | 0.84 | ADORA3 (0.40) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780837 | 0.83 | L3MBTL1 (0.45) | ADORA3ADORA2AADORA2BADORA1MCHR1 | |
| SCHEMBL8780919 | 0.83 | HRH3 (0.41) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780862 | 0.82 | KCNH2 (0.59) | SLC6A4KCNH2 | |
| SCHEMBL8780946 | 0.81 | ADORA2A (0.43) | ADORA3ADORA2AADORA2BADORA1KCNH2 | |
| SCHEMBL8780798 | 0.81 | BCHE (0.50) | SLC6A4SLC6A3ADORA3KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |