Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780802 | 0.93 | L3MBTL1 (0.44) | L3MBTL1GAAMAOBHRH3PKM | |
| Hydrochloric Acid SCHEMBL8781133 | 0.92 | L3MBTL1 (0.43) | L3MBTL1GAAMAOBHRH3PKM | |
| SCHEMBL8780798 | 0.89 | BCHE (0.50) | L3MBTL1EBPSIGMAR1HRH3MCHR1 | |
| SCHEMBL8781045 | 0.87 | MAOB (0.49) | L3MBTL1GAAMAOBHRH3PKM | |
| SCHEMBL8780993 | 0.86 | THRA (0.40) | MAOBSIGMAR1HRH3MCHR1LMNA | |
| SCHEMBL8780789 | 0.86 | ADORA2A (0.41) | HRH3MCHR1PKMADORA3ADORA2A | |
| SCHEMBL8780829 | 0.86 | RIPK2 (0.43) | MAOBEBPSIGMAR1HRH3MCHR1 | |
| SCHEMBL8780892 | 0.86 | RXFP1 (0.42) | HRH3MCHR1ADORA3ADORA2AADORA2B | |
| SCHEMBL8780727 | 0.84 | L3MBTL1 (0.44) | L3MBTL1GAAMAOBHRH3PKM | |
| SCHEMBL8780756 | 0.84 | ADORA3 (0.40) | MCHR1ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |