Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 3/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780998 | 0.91 | SLC6A4 (0.42) | KCNH2MCHR1ADORA3ADORA2AADORA2B | |
| SCHEMBL8780892 | 0.89 | RXFP1 (0.42) | KCNH2MCHR1ADORA3ADORA2AADORA2B | |
| SCHEMBL8780789 | 0.87 | ADORA2A (0.41) | KCNH2MCHR1ADORA3ADORA2AADORA2B | |
| SCHEMBL8780829 | 0.87 | RIPK2 (0.43) | KCNH2MCHR1ADORA3ADORA2AADORA2B | |
| SCHEMBL8780756 | 0.85 | ADORA3 (0.40) | KCNH2MCHR1ADORA3ADORA2AADORA2B | |
| SCHEMBL8780837 | 0.84 | L3MBTL1 (0.45) | MCHR1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8780919 | 0.84 | HRH3 (0.41) | KCNH2MCHR1ADORA3ADORA2AADORA2B | |
| SCHEMBL8780862 | 0.83 | KCNH2 (0.59) | KCNH2ALK | |
| SCHEMBL8780946 | 0.82 | ADORA2A (0.43) | KCNH2MCHR1ADORA3ADORA2AADORA2B | |
| SCHEMBL8780798 | 0.82 | BCHE (0.50) | KCNH2MCHR1ADORA3MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |