Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.50 |
| ▸ | ACHE | P22303 | 9/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | EBP | Q15125 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780837 | 0.89 | L3MBTL1 (0.45) | BCHEACHEEBPSIGMAR1ADORA3 | |
| SCHEMBL8780892 | 0.83 | RXFP1 (0.42) | KCNH2KMT2AESR1ADORA3MAPT | |
| SCHEMBL8780789 | 0.83 | ADORA2A (0.41) | KCNH2KMT2AADORA3KDM4EMAPT | |
| SCHEMBL8780829 | 0.83 | RIPK2 (0.43) | KCNH2KMT2AEBPSIGMAR1ADORA3 | |
| SCHEMBL8780802 | 0.82 | L3MBTL1 (0.44) | BCHEACHEKDM4EMAPTHRH3 | |
| SCHEMBL8780909 | 0.82 | KCNH2 (0.42) | KCNH2KMT2AADORA3MAPTHRH3 | |
| SCHEMBL8780756 | 0.82 | ADORA3 (0.40) | KCNH2KMT2AADORA3MAPTMCHR1 | |
| Hydrochloric Acid SCHEMBL8781133 | 0.81 | L3MBTL1 (0.43) | BCHEACHEKDM4EMAPTHRH3 | |
| SCHEMBL8780998 | 0.81 | SLC6A4 (0.42) | KCNH2KMT2AADORA3SLC6A4SLC6A3 | |
| SCHEMBL9429126 | 0.81 | BCHE (0.51) | BCHEACHEKCNH2SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |