Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8781133 | 0.99 | L3MBTL1 (0.43) | L3MBTL1GAABCHEACHEMAOB | |
| SCHEMBL8780837 | 0.93 | L3MBTL1 (0.45) | L3MBTL1GAABCHEACHEMAOB | |
| SCHEMBL8780776 | 0.86 | MAOA (0.37) | GAABCHEACHEMAOBMAPT | |
| SCHEMBL8781045 | 0.86 | MAOB (0.49) | L3MBTL1GAAMAOBALDH1A1MAPT | |
| SCHEMBL8780727 | 0.84 | L3MBTL1 (0.44) | L3MBTL1GAAMAOBALDH1A1MAPT | |
| SCHEMBL8780890 | 0.83 | PKM (0.52) | ALDH1A1PKMHRH3 | |
| SCHEMBL8780798 | 0.82 | BCHE (0.50) | L3MBTL1BCHEACHEMAPTHRH3 | |
| SCHEMBL8780917 | 0.81 | NPC1 (0.49) | ACHEALDH1A1HRH3 | |
| SCHEMBL8780993 | 0.80 | THRA (0.40) | MAOBTHRATHRBALDH1A1HRH3 | |
| SCHEMBL8780815 | 0.80 | ADORA2A (0.38) | BCHEACHEMAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |