Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780837 | 0.86 | L3MBTL1 (0.45) | MCHR1MAOBLMNASCN1ASCN2A | |
| SCHEMBL8780841 | 0.85 | ALDH1A1 (0.43) | MCHR1KMT2AALDH1A1HTR2AHTR2C | |
| SCHEMBL8780783 | 0.84 | HTR1D (0.41) | MCHR1KMT2AALDH1A1HTR2CBIRC5 | |
| SCHEMBL8780758 | 0.82 | LMNA (0.56) | MCHR1ALDH1A1MAOBKDM4ELMNA | |
| SCHEMBL8780796 | 0.81 | KDM4E (0.41) | MCHR1ALDH1A1HTR2AHTR2CBIRC5 | |
| SCHEMBL8780802 | 0.80 | L3MBTL1 (0.44) | THRATHRBALDH1A1MAOBKDM4E | |
| SCHEMBL8780875 | 0.79 | ALDH1A1 (0.45) | MCHR1KMT2AALDH1A1HTR2AHTR2C | |
| SCHEMBL8780892 | 0.79 | RXFP1 (0.42) | MCHR1KMT2AKCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL8781133 | 0.79 | L3MBTL1 (0.43) | THRATHRBALDH1A1MAOBKDM4E | |
| SCHEMBL8780811 | 0.79 | MAOB (0.41) | MCHR1ALDH1A1HTR2AHTR2CMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |