Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780892 | 0.86 | RXFP1 (0.42) | KMT2AKCNH2MCHR1 | |
| SCHEMBL8780758 | 0.85 | LMNA (0.56) | HTR1DHTR1BL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8780993 | 0.84 | THRA (0.40) | ALDH1A1KMT2AKDM4EKCNH2MCHR1 | |
| SCHEMBL8780946 | 0.83 | ADORA2A (0.43) | KMT2AKDM4EKCNH2MCHR1 | |
| SCHEMBL8780841 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2AKDM4EMCHR1BIRC5 | |
| SCHEMBL8780909 | 0.80 | KCNH2 (0.42) | KMT2AKCNH2MCHR1 | |
| SCHEMBL8780829 | 0.80 | RIPK2 (0.43) | KMT2AKDM4EKCNH2MCHR1 | |
| SCHEMBL8780789 | 0.80 | ADORA2A (0.41) | KMT2AKDM4EKCNH2MCHR1 | |
| SCHEMBL8780998 | 0.79 | SLC6A4 (0.42) | KMT2AKCNH2MCHR1POLB | |
| SCHEMBL8780798 | 0.79 | BCHE (0.50) | L3MBTL1KMT2AKDM4EKCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |