Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780875 | 0.94 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAMCHR1MAOB | |
| SCHEMBL8780758 | 0.90 | LMNA (0.56) | ALDH1A1KDM4ELMNAMCHR1MAOB | |
| SCHEMBL8780796 | 0.89 | KDM4E (0.41) | ALDH1A1KDM4ELMNAMCHR1MAOB | |
| SCHEMBL8780768 | 0.89 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL8780811 | 0.86 | MAOB (0.41) | ALDH1A1KDM4ELMNAMCHR1MAOB | |
| SCHEMBL8780993 | 0.85 | THRA (0.40) | ALDH1A1KDM4ELMNAMCHR1MAOB | |
| SCHEMBL8780892 | 0.83 | RXFP1 (0.42) | MCHR1HRH3KMT2A | |
| SCHEMBL8780783 | 0.82 | HTR1D (0.41) | ALDH1A1KDM4ELMNAMCHR1HTR2C | |
| SCHEMBL8780946 | 0.81 | ADORA2A (0.43) | KDM4EMCHR1MAOBKMT2A | |
| SCHEMBL8780837 | 0.81 | L3MBTL1 (0.45) | LMNAMCHR1MAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |