Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA known ✓ | P10827 | 1/20 | 0.40 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.40 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | F3 | P13726 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741724 | 0.90 | KCNH2 (0.38) | THRATHRBKCNH2BIDMCL1 | |
| SCHEMBL11143499 | 0.88 | KCNH2 (0.36) | THRATHRBKCNH2BIDMCL1 | |
| SCHEMBL10556157 | 0.86 | KCNH2 (0.43) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL285064 | 0.86 | KCNH2 (0.43) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL18139166 | 0.86 | KCNH2 (0.43) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL18140341 | 0.86 | KCNH2 (0.43) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL18140770 | 0.86 | KCNH2 (0.43) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL18140556 | 0.86 | KCNH2 (0.43) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL2232098 | 0.86 | KCNH2 (0.43) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL18139253 | 0.86 | KCNH2 (0.43) | KCNH2BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12025544-B2 | Droplet particle, and method and device for producing droplet particle | OSAKA UNIVERSITY (JP) | 2024-07-02 | — | — | US | disclosed |
| EP-3550279-B1 | METHOD FOR GENERATING DROPLET PARTICLES | KIMOTO ELECTRIC CO LTD (JP) | 2023-05-10 | — | — | EP | disclosed |
| US-20210223147-A1 | DROPLET PARTICLE, AND METHOD AND DEVICE FOR PRODUCING DROPLET PARTICLE | KIMOTO ELECTRIC CO., LTD. (JP) | 2021-07-22 | — | — | US | disclosed |
| EP-3550279-A1 | DROPLET PARTICLES, AND METHOD AND DEVICE FOR GENERATING DROPLET PARTICLES | Kimoto Electric Co., Ltd. (JP) | 2019-10-09 | — | — | EP | disclosed |
| US-8128712-B2 | Process for protecting the colors of colored textile articles or for providing crease resistance to textile articles | RHODIA CHIMIE (FR) | 2012-03-06 | — | — | US | disclosed |
| US-20110028376-A1 | PROCESS FOR PROTECTING THE COLORS OF COLORED TEXTILE ARTICLES OR FOR PROVIDING CREASE RESISTANCE TO TEXTILE ARTICLES | RHODIA CHIMIE (FR) | 2011-02-03 | — | — | US | disclosed |
| US-20080263788-A1 | PROCESS FOR PROTECTING THE COLORS OF COLORED TEXTILE ARTICLES OR FOR PROVIDING CREASE RESISTANCE TO TEXTILE ARTICLES | RHODIA CHIMIE (FR) | 2008-10-30 | — | — | US | disclosed |
| US-20070191254-A1 | Composition based on anionic polysaccharide for fabric care | HARRISON IAN | 2007-08-16 | — | — | US | disclosed |