Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794072 | 0.81 | SIGMAR1 (0.41) | SIGMAR1LTA4HALDH1A1TDP1KDM4E | |
| SCHEMBL5414053 | 0.81 | SLC6A4 (0.54) | SIGMAR1LTA4HALDH1A1TDP1KDM4E | |
| SCHEMBL7301442 | 0.81 | SIGMAR1 (0.54) | SIGMAR1LTA4HALDH1A1TDP1KDM4E | |
| SCHEMBL28347287 | 0.80 | ALDH1A1 (0.60) | SIGMAR1LTA4HALDH1A1TDP1ABCB1 | |
| SCHEMBL28347286 | 0.80 | ALDH1A1 (0.60) | SIGMAR1LTA4HALDH1A1TDP1ABCB1 | |
| SCHEMBL2355634 | 0.78 | LTA4H (0.75) | SIGMAR1LTA4HTDP1ABCB1KMT2A | |
| SCHEMBL5322499 | 0.78 | SLC6A4 (0.50) | LTA4HALDH1A1LDHAKMT2AMEN1 | |
| SCHEMBL18063436 | 0.78 | ALDH1A1 (0.58) | SIGMAR1LTA4HALDH1A1TDP1KDM4E | |
| SCHEMBL6176616 | 0.77 | MMP3 (0.60) | ALDH1A1PPARGPPARALDHAKMT2A | |
| SCHEMBL22431469 | 0.77 | SIGMAR1 (0.64) | SIGMAR1ALDH1A1KDM4EMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205639-B1 | AGENT FOR INTRODUCING A PROTECTING GROUP FOR HYDROXY GROUP AND/OR FOR MERCAPTO GROUP | UNIV KYUSHU NAT UNIV CORP (JP) | 2021-08-11 | — | — | EP | disclosed |
| US-10160694-B2 | Agent for introducing protecting group for hydroxy group and/or mercapto group | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2018-12-25 | — | — | US | disclosed |
| US-20170305809-A1 | AGENT FOR INTRODUCING PROTECTING GROUP FOR HYDROXY GROUP AND/OR MERCAPTO GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| EP-3205639-A1 | PROTECTING-GROUP INTRODUCING AGENT FOR HYDROXY GROUP AND/OR MERCAPTO GROUP | Kyushu University, National University Corporation (JP) | 2017-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160694-B2 | Agent for introducing protecting group for hydroxy group and/or mercapto group | GRHPR, AOX1, MSRB3 | SIGMAR1 522/4885LTA4H 560/4885ALDH1A1 134/4885 |
| US-20170305809-A1 | AGENT FOR INTRODUCING PROTECTING GROUP FOR HYDROXY GROUP AND/OR MERCAPTO GROUP | GRHPR, AOX1, MSRB3 | SIGMAR1 522/4885LTA4H 560/4885ALDH1A1 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.