Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799666 | 0.90 | GHSR (0.42) | PTGS2GHSRTSHRMAPK1ALDH1A1 | |
| SCHEMBL8800324 | 0.88 | MAOB (0.43) | GHSRALDH1A1L3MBTL1KMT2ANPSR1 | |
| SCHEMBL8800035 | 0.88 | GHSR (0.40) | LMNAGHSRKMT2ATHRBPOLB | |
| SCHEMBL8800451 | 0.85 | TYK2 (0.42) | LMNAGHSRALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8801121 | 0.83 | GPR35 (0.39) | LMNAGHSRTSHRALDH1A1KMT2A | |
| SCHEMBL7816803 | 0.81 | PTGS2 (0.39) | PTGS2LMNAGHSRTSHRMAPK1 | |
| SCHEMBL8799385 | 0.80 | GHSR (0.38) | GHSRALDH1A1THRBRAB9A | |
| SCHEMBL7816603 | 0.80 | MEN1 (0.38) | GHSRKMT2ATHRBPOLBRAB9A | |
| SCHEMBL7817213 | 0.80 | MEN1 (0.39) | LMNAGHSRALDH1A1KMT2ANPSR1 | |
| SCHEMBL8799508 | 0.79 | GPR35 (0.41) | PTGS2GHSRKMT2ATHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |