Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | PTGIS | Q16647 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799514 | 0.81 | TSHR (0.50) | ALDH1A1HPGDMAPTKDM4ECYP3A4 | |
| SCHEMBL9142431 | 0.79 | MASP2 (0.51) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9035461 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDNPSR1TUBB4ATUBB | |
| SCHEMBL8800375 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL875441 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL8799454 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTTRPV1 | |
| SCHEMBL8799459 | 0.74 | PDK1 (0.55) | ALDH1A1FBP1TUBB4ATUBBTUBA3C | |
| SCHEMBL27028620 | 0.72 | PDK1 (0.41) | ALDH1A1NPSR1FBP1TUBB4ATUBB | |
| SCHEMBL25252959 | 0.71 | HPSE (0.52) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL9035577 | 0.69 | ALDH1A1 (0.45) | ALDH1A1NPSR1FBP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482771-B1 | Heterocyclic acids | ZENECA LTD (GB) | 1997-06-18 | — | — | EP | disclosed |
| US-5410064-A | Thromboxane A2 antagonists and inhibitors of thromboxane A2 synthase | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-04-25 | — | — | US | disclosed |
| US-5219874-A | Heterocyclic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-15 | — | — | US | disclosed |
| EP-0482771-A2 | Heterocyclic acids | ZENECA LIMITED (GB) | 1992-04-29 | — | — | EP | disclosed |