Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554822 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TDP1HTTKMT2ARAB9A | |
| SCHEMBL8799514 | 0.80 | TSHR (0.50) | ALDH1A1TDP1HPGDLMNAMAPT | |
| SCHEMBL28119886 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TDP1HTTKMT2ARAB9A | |
| SCHEMBL19877863 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TDP1HTTKMT2ARAB9A | |
| SCHEMBL9142431 | 0.77 | MASP2 (0.51) | ALDH1A1TDP1KMT2AHPGDLMNA | |
| SCHEMBL9035461 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL875440 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1HTTKMT2ARAB9A | |
| SCHEMBL9034174 | 0.76 | TSHR (0.49) | ALDH1A1TDP1HTTKMT2ARAB9A | |
| SCHEMBL8799443 | 0.76 | TBXAS1 (0.38) | ALDH1A1KMT2AL3MBTL1HPGDLMNA | |
| SCHEMBL7919545 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TDP1HTTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214994-A1 | (3-FLUORO-2-HYDROXY)PROPYL-FUNCTIONALIZED ARYL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR THE DIAGNOSIS OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASES | FUTURECHEM CO., LTD. (KR) | 2012-08-23 | — | — | US | claimed |
| US-5837873-A | PROTECTED OXYDIAMINES | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | claimed |
| EP-0384523-A2 | New gem-diamino derivatives and their use in the synthesis of retro-inverso peptides | ENIRICERCHE S.p.A. (IT) | 1990-08-29 | — | — | EP | claimed |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | MELINTA SUBSIDIARY CORP. (US) | 2024-06-04 | — | — | US | disclosed |
| CN-111556872-B | Synthesis of borate derivatives and uses thereof | 梅琳塔治疗公司 | 2024-05-10 | — | — | CN | disclosed |
| US-11975110-B2 | Cationic polymers | TRANSLATE BIO, INC. (US) | 2024-05-07 | — | — | US | disclosed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-4356736-A2 | SYNTHESIS OF BORONATE SALTS | Melinta Therapeutics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3604316-B1 | SYNTHESIS OF BORONATE SALTS | MELINTA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20230114064-A1 | NOVEL HETEROAROMATIC SILICON-FLUORIDE-ACCEPTORS USEFUL FOR 18F LABELING OF MOLECULES AND BIOMOLECULES, AND METHODS OF PREPARING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-13 | — | — | US | disclosed |
| US-20210113483-A1 | Cationic Polymers | TRANSLATE BIO, INC. | 2021-04-22 | — | — | US | disclosed |
| US-4539155-A | New peptide, process for preparation thereof and use thereof | FUISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0057412-B1 | PEPTIDE, PROCESS FOR PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-05-22 | — | — | EP | disclosed |
| EP-0027260-B1 | PEPTIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-13 | — | — | EP | disclosed |
| US-4504584-A | PEPTIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-12 | — | — | US | disclosed |
| US-4458078-A | SYNTHESIS OF OLIGOPEPTIDES | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-07-03 | — | — | US | disclosed |
| US-4427581-A | BACTERICIDES, FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| EP-0057412-A1 | Peptide, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-08-11 | — | — | EP | disclosed |
| US-4311640-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-01-19 | — | — | US | disclosed |
| EP-0025842-A2 | Peptides, process for their preparation, their pharmaceutical compositions and their intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113483-A1 | Cationic Polymers | NSUN3, RNMT, POLRMT | ALDH1A1 3420/4885TDP1 397/4885HTT 819/4885 |
| US-20230114064-A1 | NOVEL HETEROAROMATIC SILICON-FLUORIDE-ACCEPTORS USEFUL FOR 18F LABELING OF MOLECULES AND BIOMOLECULES, AND METHODS OF PREPARING SAME | KIT, FER, FUT8 | ALDH1A1 1668/4885TDP1 1904/4885HTT 2908/4885 |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | ADH5, ADH1A, ADH7 | ALDH1A1 69/4885TDP1 1727/4885HTT 4861/4885 |
| US-20120214994-A1 | (3-FLUORO-2-HYDROXY)PROPYL-FUNCTIONALIZED ARYL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR THE DIAGNOSIS OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASES | APP, FABP7, SLC3A2 | ALDH1A1 2595/4885TDP1 2206/4885HTT 56/4885 |
| US-11975110-B2 | Cationic polymers | NSUN3, RNMT, POLRMT | ALDH1A1 3420/4885TDP1 397/4885HTT 819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.