Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800075 | 0.88 | ITGB1 (0.39) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL8800451 | 0.88 | TYK2 (0.42) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL8808952 | 0.84 | CRHBP (0.43) | ALDH1A1LMNAMAPTNPSR1HPGD | |
| SCHEMBL8800035 | 0.84 | GHSR (0.40) | LMNAMAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL8799385 | 0.80 | GHSR (0.38) | ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL8801121 | 0.80 | GPR35 (0.39) | ALDH1A1LMNAMAPTNPSR1HPGD | |
| SCHEMBL8799666 | 0.79 | GHSR (0.42) | ALDH1A1MAPTNPSR1L3MBTL1MEN1 | |
| SCHEMBL8800220 | 0.78 | CYP3A4 (0.35) | ALDH1A1LMNAHPGDCDC25B | |
| SCHEMBL8799546 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL7816603 | 0.76 | MEN1 (0.38) | MAPTSMN1; SMN2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |