Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798766 | 0.90 | CYP3A4 (0.37) | MAPK1SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL8803294 | 0.88 | MMP8 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8798260 | 0.83 | LTA4H (0.38) | TBXAS1MAPK1SMN1; SMN2CYP3A4FKBP1A | |
| SCHEMBL8799648 | 0.82 | MAPK1 (0.36) | TBXAS1MAPK1SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL8799066 | 0.82 | LMNA (0.39) | SMN1; SMN2 | |
| SCHEMBL8799774 | 0.80 | CYP17A1 (0.35) | ALDH1A1 | |
| SCHEMBL8798844 | 0.80 | DPP4 (0.40) | MAPK1SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL8329548 | 0.80 | LTA4H (0.41) | ALDH1A1 | |
| SCHEMBL8799959 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8798973 | 0.78 | FKBP1A (0.37) | ALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |