Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805753 | 0.88 | PTGES (0.38) | NPC1RAB9ALMNACASP3SENP8 | |
| SCHEMBL9866354 | 0.79 | MPL (0.40) | NPC1RAB9AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL18377841 | 0.77 | ADORA3 (0.53) | NPC1RAB9ALMNACASP3SENP8 | |
| SCHEMBL8803518 | 0.73 | KDM4E (0.42) | KDM4EMEN1GAAKMT2A | |
| SCHEMBL8947073 | 0.72 | TTR (0.46) | NPC1RAB9ATTRPIM1PIM3 | |
| SCHEMBL2213825 | 0.69 | ADORA3 (0.59) | NPC1RAB9ALMNACASP3SENP8 | |
| SCHEMBL23042515 | 0.69 | RAB9A (0.50) | NPC1RAB9ALMNACASP3SENP7 | |
| SCHEMBL8805859 | 0.69 | IDH1 (0.38) | NPC1RAB9ALMNACASP3SENP8 | |
| SCHEMBL6529431 | 0.67 | PSMD14 (0.30) | — | |
| SCHEMBL6530965 | 0.67 | CCR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751943-A1 | TRIAZOLE COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025107-A1 | TRIAZOLE COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1995-09-21 | — | — | WO | disclosed |