Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804876 | 0.87 | REN (0.39) | RENL3MBTL1KDM4EATMPTGDR2 | |
| SCHEMBL8805650 | 0.86 | REN (0.41) | RENL3MBTL1KDM4EATMALDH1A1 | |
| SCHEMBL8805131 | 0.79 | KDM4E (0.40) | L3MBTL1KDM4EATMPTGDR2IL1R1 | |
| SCHEMBL8805724 | 0.76 | REN (0.40) | RENL3MBTL1KDM4EIL1R1MEN1 | |
| SCHEMBL3161134 | 0.71 | REN (0.42) | RENKDM4EMEN1MAPTKMT2A | |
| SCHEMBL16484321 | 0.70 | KDM4E (0.67) | L3MBTL1KDM4EATMMEN1MAPT | |
| SCHEMBL8805617 | 0.69 | PLA2G2A (0.44) | L3MBTL1KDM4EATMPTGDR2IL1R1 | |
| SCHEMBL17228253 | 0.68 | KDM4E (0.59) | L3MBTL1KDM4EATMMEN1MAPT | |
| SCHEMBL17228252 | 0.68 | KDM4E (0.52) | L3MBTL1KDM4EATMMEN1MAPT | |
| SCHEMBL1922920 | 0.66 | MPO (0.42) | KDM4EMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |