Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805724 | 0.90 | REN (0.40) | RENALOX12PDE7ACYP1A2ALDH1A1 | |
| SCHEMBL8804502 | 0.86 | REN (0.41) | RENPDE7AALDH1A1RAB9AKDM4E | |
| SCHEMBL8804876 | 0.74 | REN (0.39) | RENALDH1A1RAB9AKDM4EATM | |
| SCHEMBL16484319 | 0.73 | KDM4E (0.59) | ALOX12CYP1A2RAB9AMDM2KDM4E | |
| SCHEMBL8804561 | 0.72 | ALOX12 (0.46) | ALOX12CYP1A2ALDH1A1CYP2C9HPGD | |
| SCHEMBL19359918 | 0.71 | L3MBTL1 (0.53) | ALOX12PDE7ACYP1A2ALDH1A1RAB9A | |
| SCHEMBL17989838 | 0.68 | L3MBTL1 (0.53) | ALOX12PDE7ACYP1A2ALDH1A1RAB9A | |
| SCHEMBL23438634 | 0.68 | KDM4E (0.52) | ALOX12CYP1A2RAB9AMDM2KDM4E | |
| SCHEMBL15630907 | 0.68 | ALOX12 (0.46) | ALOX12CYP1A2RAB9AMDM2KDM4E | |
| SCHEMBL12091851 | 0.68 | ABCB1 (0.51) | ALOX12CYP1A2ALDH1A1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |