Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804561 | 0.85 | ALOX12 (0.46) | PLA2G2APTGDR2HDAC6ALDH1A1MEN1 | |
| SCHEMBL24856039 | 0.74 | ALDH1A1 (0.58) | PLA2G2APTGDR2HDAC6ALDH1A1MEN1 | |
| SCHEMBL8804876 | 0.74 | REN (0.39) | PTGDR2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8805131 | 0.73 | KDM4E (0.40) | PTGDR2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5226018 | 0.73 | IL1R1 (0.68) | PLA2G2APTGDR2HDAC6ALDH1A1MEN1 | |
| SCHEMBL16484321 | 0.72 | KDM4E (0.67) | ALDH1A1MEN1MAPTKMT2AHSP90AA1 | |
| Hydrochloric Acid SCHEMBL31109106 | 0.72 | ALDH1A1 (0.68) | PLA2G2APTGDR2HDAC6ALDH1A1MEN1 | |
| SCHEMBL12352483 | 0.71 | PLA2G2A (0.56) | PLA2G2AHDAC6ALDH1A1MEN1MAPT | |
| SCHEMBL8804502 | 0.69 | REN (0.41) | PTGDR2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11126713 | 0.68 | PLA2G4A (0.53) | PLA2G2APTGDR2HDAC6ALDH1A1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |