Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.39 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804502 | 0.87 | REN (0.41) | RENIL1R1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL8805724 | 0.80 | REN (0.40) | RENIL1R1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL8805650 | 0.74 | REN (0.41) | RENALDH1A1L3MBTL1KDM4EATM | |
| SCHEMBL8805617 | 0.74 | PLA2G2A (0.44) | IL1R1ALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL8805131 | 0.72 | KDM4E (0.40) | IL1R1ALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL3161134 | 0.68 | REN (0.42) | RENALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL16484321 | 0.67 | KDM4E (0.67) | ALDH1A1L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL17228253 | 0.65 | KDM4E (0.59) | ALDH1A1L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL17228252 | 0.64 | KDM4E (0.52) | ALDH1A1L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1922920 | 0.62 | MPO (0.42) | ALDH1A1MEN1MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |