Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805617 | 0.85 | PLA2G2A (0.44) | PLA2G2AGSRPTGDR2MAPK1HDAC6 | |
| SCHEMBL11126713 | 0.83 | PLA2G4A (0.53) | ALOX12MDM2PLA2G2APTGDR2RAB9A | |
| SCHEMBL11098148 | 0.82 | PLA2G2A (0.46) | ALOX12MDM2PLA2G2AGSRPTGDR2 | |
| SCHEMBL11035273 | 0.81 | TBXAS1 (0.51) | ALOX12PLA2G2APTGDR2PLA2G4A | |
| SCHEMBL8805724 | 0.80 | REN (0.40) | ALOX12MDM2RAB9AGAAMAPK1 | |
| SCHEMBL16484319 | 0.75 | KDM4E (0.59) | ALOX12MDM2GSRRAB9ACYP11B2 | |
| SCHEMBL8805650 | 0.72 | REN (0.41) | ALOX12MDM2GSRRAB9ACYP1A2 | |
| SCHEMBL24856039 | 0.71 | ALDH1A1 (0.58) | PLA2G2APTGDR2GAAHDAC6GFER | |
| SCHEMBL20135887 | 0.70 | ALOX12 (0.57) | ALOX12MDM2GSRRAB9AGAA | |
| SCHEMBL5226018 | 0.70 | IL1R1 (0.68) | PLA2G2APTGDR2GAAHDAC6GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |