Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480309 | 0.77 | RIPK1 (0.41) | RIPK1LMNAHRH1HTR2ASLC6A3 | |
| SCHEMBL704603 | 0.77 | RIPK1 (0.41) | RIPK1LMNAHRH1HTR2ASLC6A3 | |
| SCHEMBL187205 | 0.77 | RIPK1 (0.41) | RIPK1LMNAHRH1HTR2ASLC6A3 | |
| SCHEMBL708031 | 0.77 | RIPK1 (0.41) | RIPK1LMNAHRH1HTR2ASLC6A3 | |
| SCHEMBL9452316 | 0.76 | RIPK1 (0.39) | RIPK1LMNAHRH1HTR2ASLC6A3 | |
| SCHEMBL343426 | 0.73 | LMNA (0.41) | RIPK1LMNAHRH1HTR2ASLC6A3 | |
| SCHEMBL5029899 | 0.72 | RIPK1 (0.43) | RIPK1LMNAHRH1HTR2ASLC6A3 | |
| SCHEMBL705924 | 0.71 | RIPK1 (0.40) | RIPK1LMNAHRH1SLC6A3SLC6A4 | |
| SCHEMBL704144 | 0.71 | ATM (0.39) | RIPK1LMNAHRH1HTR2ASLC6A3 | |
| SCHEMBL708398 | 0.70 | LMNA (0.39) | RIPK1LMNAHRH1HTR2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |