SCHEMBL8817697

SCHEMBL8817697

c1ccc(-c2cc(-c3ccccc3)nc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5cc7c(cc5n6-c5ccccc5)c5ccccc5n7-c5ccccc5)ccc43)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
KDM4E B2RXH2 2/20 0.44
ATM Q13315 1/20 0.44
PTGER4 P35408 1/20 0.36
TSPO P30536 1/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
DHODH Q02127 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPY5R Q15761 1/20 0.34
IL1R1 P14778 1/20 0.33
HDAC4 P56524 1/20 0.33
MCL1 Q07820 1/20 0.33
HTT P42858 1/20 0.33
PTGES O14684 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11998234 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL15371712 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL11998229 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL15748607 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL14212374 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL6373523 0.96 L3MBTL1 (0.43) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL6373266 0.96 L3MBTL1 (0.43) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL15748517 0.96 L3MBTL1 (0.43) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL18717872 0.95 L3MBTL1 (0.44) L3MBTL1KDM4EATMPTGER4TSPO
SCHEMBL15748464 0.95 L3MBTL1 (0.44) L3MBTL1KDM4EATMPTGER4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 US disclosed
US-20140077179-A1 NOVEL COMPOUND FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-03-20 US disclosed
US-20140077179-A1 NOVEL COMPOUND FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-03-20 US disclosed
WO-2012067425-A1 NOVEL COMPOUND FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 L3MBTL1 737/4885KDM4E 2107/4885ATM 1217/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 L3MBTL1 566/4885KDM4E 2766/4885ATM 1838/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 L3MBTL1 737/4885KDM4E 2107/4885ATM 1217/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 L3MBTL1 2484/4885KDM4E 2736/4885ATM 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.