Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253188 | 0.83 | HSD17B10 (0.52) | ESR1ESR2KMT2AMEN1LMNA | |
| SCHEMBL6155017 | 0.79 | LMNA (0.54) | ESR1ESR2KMT2AMEN1LMNA | |
| SCHEMBL8827881 | 0.79 | LMNA (0.39) | ESR1ESR2KMT2AMEN1LMNA | |
| SCHEMBL4624103 | 0.78 | KDM4E (0.50) | ESR1ESR2KMT2AMEN1LMNA | |
| SCHEMBL7707716 | 0.77 | SLC22A6 (0.44) | ESR1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL44289 | 0.76 | MAPT (0.33) | LMNAKDM4EHSD17B10PARP1POLB | |
| SCHEMBL8844752 | 0.76 | MAPT (0.33) | LMNAKDM4EPARP1POLBMAPT | |
| SCHEMBL7397635 | 0.75 | SLC6A3 (0.44) | ESR1ESR2KMT2AMEN1LMNA | |
| SCHEMBL44290 | 0.75 | LMNA (0.35) | KMT2AMEN1LMNAKDM4EPOLB | |
| SCHEMBL20479976 | 0.74 | ENPP2 (0.31) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702952-A | Labelled boronic acid derivatives | AXIS BIOCHEMICALS ASA (NO) | 1997-12-30 | — | — | US | disclosed |
| US-5631364-A | Labelled boronic acid derivatives | AXIS BIOCHEMICALS ASA (NO) | 1997-05-20 | — | — | US | disclosed |