Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832794 | 0.85 | SIGMAR1 (0.33) | SIGMAR1ECE1 | |
| SCHEMBL8833259 | 0.82 | ECE1 (0.34) | SIGMAR1ECE1 | |
| SCHEMBL9215991 | 0.82 | ECE1 (0.34) | SIGMAR1ECE1 | |
| SCHEMBL8832733 | 0.82 | FAAH (0.34) | SIGMAR1ECE1 | |
| SCHEMBL8833376 | 0.80 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL9220610 | 0.80 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL8832597 | 0.79 | ECE1 (0.36) | SIGMAR1ECE1 | |
| SCHEMBL9027366 | 0.79 | ECE1 (0.33) | SIGMAR1ECE1 | |
| SCHEMBL8833409 | 0.79 | ECE1 (0.32) | SIGMAR1ECE1 | |
| SCHEMBL8833217 | 0.79 | ALDH1A1 (0.34) | SIGMAR1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608056-A | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021186-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-28 | — | — | WO | disclosed |